Synthesis of some new porphyrins and their metalloderivatives as potential sensitizers in photo-dynamic therapy.

Synthesis and Application of New Gadolinium-Porphyrins as Potential MR Imaging Contrast Agents for Cancer Detection in Nude Mice

Two new potential magnetic resonance imaging contrast agents, Gd-hematoporphyrin (Gd-H) and Gd-tetra-carboranylmethoxyphenyl-porphyrin (Gd TCP), were synthesized and applied to nude mice with human melanoma (MM 138) xenografts. These agents showed a high relaxivity because of their greater potential to coordinate water molecules. The reduction of T1 relaxation times of 16 and 21% was observed i...

Preparation of Symmetrical Tetraphenyl Porphyrin Metal Complexes and Their Spectroscopic Studies

Porphyrins molecules are gaining importance in the present era. Porphyrins are important part of biological molecules like hemoglobin and chlorophyll .Photo system 1 and photo system 2 is important sunlight trap in chloroplast. Electron transport chain is a series of chemical reaction in which energy is formed in the form of ATP (Adenosine triphosphate).The members of electron transport chains ...

Use of novel cardanol-porphyrin hybrids and their TiO₂-based composites for the photodegradation of 4-nitrophenol in water.

Cardanol, a well known hazardous byproduct of the cashew industry, has been used as starting material for the synthesis of useful differently substituted "cardanol-based" porphyrins and their zinc(II), copper(II), cobalt(II) and Fe(III) complexes. Novel composites prepared by impregnation of polycrystalline TiO₂ powder with an opportune amount of "cardanol-based" porphyrins, which act as sensit...

Hplc Separation of Porphine, Selected Porphyrins and Their Metalloderivatives

Synthesis, Reprecipitation Method and Pharmacological Potency of Free Porphyrin Based Nanoparticles

We have designed and synthesized a new symmetrical porphyrins 3a-d and their nanoparticles based on extended π-conjugation concept. The new sensitizers were fully characterized by CHN analysis, UV-Vis., H-NMR, TEM and Mass spectroscopy. The new sensitizers and their nanoparticles were evaluated as antitumor activity against HepG2, WI-38, VERO and MCF-7 cell lines. It was found that porphyrin na...